Sir Trevor McDonald

Although four out of five children with leukaemia now survive, for some children there is no hope of a cure.You can donate to Sir Trevor's appeal here

Sir Trevor McDonald is appealing for your help to give children hope of a cure.

We have pledged to support a £1 million body of work at Great Ormond Street Hospital.

Four research projects using ground-breaking gene therapy to try and save the lives of more leukaemic children.

The new treatments aim to use the body’s own immune system to fight leukaemia.

Powerful drugs used in existing treatments can cause serious long-term effects: heart problems, infertility and secondary cancers.

Sometimes, the treatments can even cause a child’s death.

Hollie O'Brien Four year old Hollie O’Brien was one such child.

Grandmother Wendy knows it's too late for her family - but hopes Hollie's memory can help spare other families the pain of such a loss.

The new treatments now being developed could have saved Hollie's life

Put simply, with new treatments doctors will be able to save more lives.

Please help us. Your support will make a huge difference and without it this work simply couldn’t continue.

For donations of £25 or more we’ll happily send you a signed, colour photo of Sir Trevor McDonald as an extra special thank you!

What you can do